This whole "smaller 2x4 carbs=better" scenario has been a source of annoyance more than once for me.
Ford in their inifinite funding, decided on two 600's for their street 427, later they used dual 715's. Now guys are building 482ci strokers and asking me about dual 390's or 450's because of some stupid Holley calculator. Lol..... right right right. The Holley calculator has one purpose, and it is to keep annoying people from calling the apathetic help line.
When asked, I'm sticking to my guns here:
>550hp dual 600's
>550hp more race oriented, dual 715's
<550hp street, dual 715's
<550 full race, 660's
Big cubes, big power street, dual 780's
If you are a tinkerer, you can blur those lines a good bit more.
The one place I like to use 1848's, 1849's or -C carbs is for the 390/410 mild cruiser that just wants the glam of 2x4's.
I am curious about dual 850cs's vs 660's with much larger (500ci + full race) engines, I just don't have any real track data for that.