In theory, yes, advancing the cam can shift the peak down a bit, retarding can go up. However, that's why I mentioned tight lashing, you could likely gain it back if you didn't like the peaks by closing that lash up.
In the end, that isn't a huge cam, despite the lazy lobes, essentially using a normal lobe measurement, I would call it a 282-ish/227 @ .050, 114 LSA on 109. 109 is a late intake valve IMO, especially on a 390, but if you compared that to a hydraulic CJ cam, those were smaller lobes but on a 114 ICL, so it's not like 109 is crazy. If you are not confident in running it early, I'd just stick it in at zero, and if it comes in later than 109, advance it a bit, if it comes in on target, run it
That being said, I do think it'd run a little stronger low and mid advanced, but if you are used to 7 inches of vacuum, we may be negotiating something that won't matter at all. That cam should have plenty of vacuum regardless