You can get the best of both worlds, performance-wise by ordering a custom ground cam with much more aggressive ramps. Less seat duration, similar duration @ 0.050", and more area under the curve.
For instance I have a solid flat tappet Compcam with 270/276 duration @ 0.020", 240/246 duration @ 0.050", and .598"/.608" lift. It peaked at 6200 rpm with 432 cubic inches. My heads are little more hogged out than yours, but you get the idea. The downside is the spring pressure required. I ended up with about 405 lbs of open pressure. I used EDM lifters to help lube the cam/lifter interface. It ran fine for about 5000 miles before I pulled the cam to put in a larger one. I ran up to 6500-6600 rpm with no problem. Titanium retainers were a big help avoiding valve float, too. What I'm getting at is you can have your cake and eat it, too. It just costs a bit more money and requires a bit more maintenance.
If your combo is the same as mine, but you have 36 more cubic inches, I would guess you'd need about 7-8 more degrees of cam duration get the same peak. However, since my heads are more heavily ported, I think you'd have to add a few degrees more on top of that. That's why I say around 252-256 degrees on the intake side could get you there, if you're using an aggressive cam lobe.
If you used the same cam lobes I did, XTQ on the intake and TL on the exhaust, then you might have a XTQ286 on the intake and a TL292 on the exhaust. That would be 256/262 degrees @ 0.050". Even though the duration is less than a Magnum 306S it has more area under the curve and will peak higher. At least I think so.
Or you could move the intensity down a step and usea TL284 on the intake and maybe a HT295on the exhaust. Thoe are 254/260 degrees @0.50 and would be easier to contol, valvetrain-wise, but still way more agressive than a magnum cam lobe.
The possiblities are almost endless. Just food for thought.
JMO,
paulie