Yes. About 20 years ago I had a 428 dynoed, with Edelbrock heads, and it liked a lot of timing. I hesitate to answer because it sounds dubious for sure and I don't want to argue what happened. But I wanted to share my experience. The key points in my mind were that it was low compression and dyno-ed on race gas. The compression ratio was about 9.2 or 9.3 to 1. I don't remember the exact octane of the race gas. 110? I don't know much about race gas, but that was what they had at the dyno and we used it to "be safe". Cam was solid flat with 276/284, 242/246. Anyway, the power kept going up as we increased timing, all the way to 45 degrees total. I got kind of freaked out at that point and stopped. As I remember I backed it off to around 40 degrees driving on the street with pump gas. It seemed to work fine. For sure we should've run it on the dyno with pump gas, too. I don't remember the quench distance on that combo. It could have been fairly large?
I know the first thing that will be mentioned is, was the balancer reading right? I think it was. I had lots of very knowlegeable engine guys around helping and we checked those things. I used the same heads, similar but different cam, same balancer, same pointer, same distributor, etc. on a later rebuild with a true 10.5:1 compression and dynoed with 91 octane pump gas, it made best power at 36-37 degrees.
I think the low compression and high octane of the original combination as dynoed wanted a lot timing. Also possibly a suboptimal quench distance? I don't know for sure about that. I know people argue about the effects of octane, burn rate, and such.......
pl