Like I said before, I'm running 2.200 intakes and 1.750 exhaust valves in my edelbrock 6005 heads. They squeak by just fine even with over .750 lift in my 4.140 bore Fe. The heads were prepared with the plans of going on a 4.250 bore fe and they may still be. However I did and certainly recommend notching the block anyway for clearance and un-shrouding the valves.
Your best bet is to install a head with gasket and valves in one cylinder with light springs. This way you can check clearance at several different lifts and also get yourself a good mark around valves in the cylinder so you can see where to ace your "notches" . I good fine carbide bit makes quick work but I prefer using a round file to set my edges of the notch then use a cartridge roll and sneak up on it. Make them not only look like they belong but in the right position as well.
JMO and how I do it.
Good luck regardless.