Yes I have. Tad over 12:1 with a tight cam that built a lot of cylinder pressure, enough that the damn thing would diesel a little when you turned the key off most summer days (on 93) unless you ran the carbs dry. 420" or so SBC and a healthy dose of nitrous, timing locked at 36° because stereotype Chevy nitrous guy. He tried WOT switch etc and was having no luck... I tapped the input on the digital 7 for a window switch basically, and had the system active around 2800 RPM. I bought a buck transducer off Amazon to supply the constant 5v to a factory GM 2 bar MAP sensor, and used the kPa readings to dial in how much meth/water came in, and when. It wasn't exactly easy to get right from a tuning standpoint but it damned sure was fun. I started with jetting the carb up on race gas and used a wide band... Had it starting to go "lean" mod range on up (13.5:1 or so) without knock ping etc. We then switched to pump and meth/water, and basically tuned from there. Most of the meth system components came from a company called "pro meth" - the guy posts on yellow bullet occasionally, and we used the "sleeper" setup I believe it's called... Basically, if you're a good enough carb guy to own a pin vice drill bit set and actually understand the air circuit, you'll be able to pull it off. I bought the kit from the guy recently and intend to run it on my FE build. The kit is in the attic or I'd post pics... Won't be coming down til I get my heads/other junk back from Blair. I'm shooting for mid 11s up to 12 on static, and 93 octane. I'm also planning to run a not so small cam, but I left that decision up to him. Personally, I think he's probably the best Ford guy in the country, that (almost) nobody has ever heard of. Well, except those of us that like rear mains that leak and having to scrub that little oil drip off the head, under the valve cover rail, every time we wash the car..
Honestly ^^^ was a hell of a lot more challenging to tune than the boosted "street" setups I've had a hand in. Then again, I couldn't just change a few numbers in a table and/or multiply the whole damn thing by a half percent at a time. Just took time and patience, as does any truly good tune up. Definitely not my first rodeo, but was *almost* fun to get my ass kicked for a few weeks.