BB, as a guy who deals in differential pressures and flow loss, how about either doing the math to compare a 5/16, 3/8 and 1/2 line with a mechanical pump or finding someone who can?
I am not being a wise-ass, I'd truly like to find out. The issue really that comes into play that I am not sure how much negative pressure on pickup side is lost over 10 feet of 3/8 versus 10 feet of 5/16 and how all the things that affect pressure loss in a pipe converts to suction and flow.
Although I agree that a 3/8 line is good insurance, or even bigger (I run 1/2 inch on my Mustang), but in my opinion, not until 500 hp do you really task the ability of a 5/16 line if you have an adequate pump. May not seem like it, but by converting a known HP into BSFCs ranging from .5-.6 into lbs/hr and that into GPH, assuming no kinds kinks, restrictions, or other baloney, would make you think that a 5/16 line with a good pump should feed more than most street/strip motors would need
Need to remember that the cars of the 60s used the fuel pumps of the 60s.
I'd also add that anyone who changes line size and pickup size, take a good look at the adapters and inverted flare seats in most pumps, rarely will you see them the same size of the line.
Now with that being said, there sure isn't any reason NOT to run a bigger fuel line, but the 400 hp motor that we were talking about had a vent problem, you could go 1/2 line and not that make his car run better. In addition, I'd expect most CJs of the day did too, as a Mustang tank uses a crappy vent setup, basically a "dent in the gas cap sealing surface" to vent the tank.
I used some basic pressure drop calculations on the pressure side and backed it into flow loss after the pump and it can surely feed even a stroker, but the pickup side of a pump is MUCH less negative pressure and is dealing with a longer line. There has to be a way to calculate, but I don't know how, are you able to?