I have a little bit different experience.
First, Barry and Jay answered your question correctly on shifting the curve down, but I don't think it was necessarily the right question for cruise mileage. If you dyno'd a 109 ICL cam then dialed it in to 109, my guess is the entire curve would be very similar with a little nod to the 109 for the peaks. So the WOT curve under power wont move much
However, would you notice part throttle response going from 109 to 106?
I think it would be very noticeable, for example, I took my 427 from 108 to 105 and it was dramatically better part throttle and gained 3 in of vacuum at idle and it was far happier in 4th gear (back when it was a single plane 427/4 speed/3.70 with a 300 adv/250@.050 108 LSA cam)
In addition, in 2001 I had a 2000 Dodge Ram EFI 360 that felt flat to me, after realizing they retarded the cam for emissions, I took it from stock 110 ICL to 106 and it picked up noticeable response down low and idled much cleaner.
In both cases, I based it off intake closing point, but even in the late 80's I used to advance stock SBC cams in trucks because they were so much happier at 4 degrees advanced. I didn't know why back then, but they did real well and after initial experimentation I kept doing it. Old school experimentation basically after hearing the old guys used to retard them for RPM.
However will you get get better gas mileage? My guess is that having the cam advanced and some careful tuning, the engine would be more efficient part throttle and therefore it would get better mileage. How much? Probably not a huge gain, but my guess, and almost a promise, is that you'd like the way it ran.