Just theoretically what would have to be done on a 500 cube FE with an iron block to support a 871 blower, it of course would be an aftermarket cross bolted block. And what kind of HP could be realized on pump gas with a 7.5:1 compression ratio. The limitations or a Roots is generally idle to 5500 rpm so the camshaft would not have to be a monster and I would say a Blue thunder high riser head would be in order along with the intake.
BDS and a few other blower specific sites like Dyers has some pretty good basic info on blower engines. One of the big issues is the huge cost of the intake, blower, drive and carb & linkage setup, something I'm sure you already know and can easily exceed $7,000 bucks.
http://www.blowerdriveservice.com/common-questions.htmlOpinions here may vary (LOL!) but:
-with a 500 CID FE, not sure one would need or want to invest in a blower as hp at even 1.25 per cube would be 625.
-you didn't mention the blower ratio or boost level. It's easy to get in trouble trying to run pump gas and any kind of boost over say 7-8 lbs or so.
-Hp wise, it's easy to get about 1.3 hp / CID with a lightly boosted 8-71 or about 650 hp with a 500 CID engine. But, one can also attain that level of hp, and more, as Jay, Barry and Brent have shown with numerous builds w/o supercharging.
-Most charger'ed cars are set-up for show as opposed to gargantuan hp levels. Still, one could easily top the 1,000 hp mark with the right parts in that 500 CID FE but now we're talking major boost levels (think: 50% and more over crank rpms) and the highest octane racing gas.
-JMO!
This site has a nice generic chart on boost /gasoline types as boost goes up.
http://www.superchargerusa.com/tech_boost_fuel.htm