I firmly believe that beer and staring in the proper order (or in cycles) almost always gets the job done

.
As far as the swap, I can't imagine how you'd hurt power as the Holley at 600 isn't too big and you're also going to aid breathing on the exhaust side to help keep things moving.
I get a bit limited here, but I would think intake charge velocity would be controlled initially by the heads and more or less regulated by the carb. Therefore things should work well IMO. I would guess that what the intake charge does between the carb and intake valves would be the key to whether performance would drop.
These are just my thoughts

, it'll be interesting to catch input from experienced Blue Thunder users.