You'd be surprised on how many aftermarket pistons have that feature. Small block stuff, all the way up to 4.300" and 4.500" stroke BBF stuff. I've never had any issue with a piston being set up that way, knock on aluminum. Was talking to one of the writers of Modified Mustangs & Fords the other day, and he has a 347 SBF with way over 100k on the clock that doesn't use any oil.
It all depends on what other components you go with on how big the price differential is. If you use premium parts and compare apples to apples, the price on going bigger isn't all that bad. If you go with Probe/Icon/Race-Tec pistons, a cast 4.250" Scat crank, and I-beam rods, the price of a 4.375" rotating assembly is going to be a good bit higher. However, if you go with a premium 4.250" setup, with Diamond pistons, a forged Scat crank, etc, etc., then the price isn't going to be much different at all, and you may end up with a cheaper setup overall.
Figure out which route you're going to go, do some shopping, and then you can make a more educated decision.