So degreeing the cam can tell you what the lobe is really doing, in the end, you can do that in the truck. However ultimately, your compression ratio does not match the cam and fuel.
That cam at 106 is going to be too small for a 10.5:1 compression, or better put, the compression is too high for that cam.
At 110 ICL, IMO, you are right on the edge for a light car, stiff gear, good fuel, which could lead you to tighter lash as we talked about before. Other band aids would be slowing down the curve, running richer, etc. However I think you are out of runway on the lash, it won't hurt to try if you want, I run my Mustang at .014 cold, but there is only so much you can do.
If you were to rock that cam back another 4 degrees or so, using a 9 position gear, at 114 I bet it would knock the edge off, and making sure it isn't hot, lean and the curve is right, would do OK on fuel.
But, later cam timing will drop idle vacuum if that's a concern.
However, if I was chasing it. I'd chase curve, plugs, and mixture now as a band aid to avoid going inside. Then resolve that I need to swap cams at some point.
A slightly larger lobe at .006, with .050 to match use of the truck, then spread the centers to meet vacuum and drivability requirements. No more messing around and you can get to what you want. That being said, to get that cam, need to get a real compression number and then degree the cam when installed.
Now there is a curve ball, because you are backing into a cam with high compression, there likely will be trade offs. A 445 in a truck is usually not a 10.5 motor, we'd be closer to 9.75-10 for a cam to match use. In fact, my own is exactly that, 9.75 with a 280 adv lobe and it does fine. That likely means you'd have to accept it being alittle more rowdy than we'd normally do it, or if you have room to still have decent quench, try to drop compression a bit, maybe both.