Random things
I had a Terminator X that had cam and crank sensors wired backwards, if you turn your distributor back and forth the correct light should correspond with the ECU. We spent two days and had Holley tech come to the dyno, to ultimately find by accident that the harness was backwards at one of the junctions.
Cam light came on distributor, crank on ECM and vice versa. I don't trust any plug now from Holley LOL. My wife and I sit down on every build and she calls out positions and colors and I check them before install
Second, if no other issue, and you have key on power to the distributor harness and the ECM, and key off power on the large wires and good grounds, almost sounds like a short in the distributor