You best buy a carb specially calibrated for E85. You're looking at nominal 9:1 more or less AFR and the quality of "E85" can vary from E70 to as much as E90 and your carb calibration will have to allow for that. At the least, Quick Fuel offers a kit with blocks. My experience so far running Methanol (close to 6:1 AFR) is that you best work with someone that knows what they are doing, or stick to running gas. Alcohol tolerates being fat easily but doesn't deal well with being too lean. Also, your mileage will go down because alcohol has less BTU/gallon than gasoline but usually makes more power because of the self cooling intake charge and the oxygen carried in the fuel. So it may not be as economical as you may expect. I can assure you that a methanol race engine is pretty stingy on fuel running down the strip at full bore (relatively speaking) but will chew the hell out of fuel just idling. My dragster will eat a full gallon just warming up. You'd expect to lose a gallon maybe making 570 HP for 6 seconds at full bore, maybe not expect that when putt-putting next to the trailer. I've seen what it takes to run full alcohol, I paid someone well to convert a 750DP to run that. The modifications to the base carb were extensive. Note - I also run a "top lube" to help prevent corrosion in the fuel system. Converting the dragster from gas to methanol cost around $1200 - pump, lines, fittings, regulator, carb, additives.
X2 on the fuel system - everything needs to be compatible with alcohol. J309 minimum spec for alcohol if I recall right. It will also chew the hell out of any raw aluminum, so make sure anything that contacts the fuel is either compatible flex/, anodized if aluminum or even stainless.
X2 on maintenance - you'll want to check your filters (use stainless 100 micron - not paper) regularly and switch back to gas for storage, or pump the entire system down, disassemble and blow out the carb with air and WD-40, pull the plugs and hose the cylinders with WD-40, spin the motor over to clear, then put the plugs back in.
"High-pressure fuel hose for clamp-type fuel-injection systems is also available. This fuel hose is SAE 30R9-rated and uses a fluoro elastomer inner liner that will withstand up to 180 psi and 300 degrees. It is approved for all fuel blends including straight methanol, and the outer coating is also ozone- and abrasion-resistant. High-pressure fuel-injection hose can also be used in low-pressure applications, but the difference in pricing may convince you to save it for where it is needed."
