You can do it in the car, in fact, in the picture below, I did it on an engine that was running that AM.
As Brent said, the more joints, turns, pieces, you go through, the more variables you introduce, but it's easily done
FWIW story behind the picture below was 12 years ago when my Mustang was a .040 427, stock stroke. I ran a Portosonic, 1000 Holley, and an old Isky EE-390, 300 adv, 250@.050, on 108 with no advance ground in, installed on 108. Ran OK, but wanted a little more street manners, so I cranked it forward.
![](http://s20.postimg.org/wbupu6ajh/Degree1.jpg)