The quadra-jet has way bigger secondaries and smaller primaries then the ford spead-bore, so no it wont fit a clev. spread-bore intake.
I use the above adapter and you can use it on any intake with the regular Holley or 4100 pattern. One word of caution, when using the open adapter, make sure the base plate screws on the Quadra-jet are locktited in place. If one of the screws comes loose it will be immediately ingested into the motor. Don't ask me how I know this. I use a thin stainless gasket under the quad just in case.