In my early college years I'd do the NY to Fla trip in my 67 390 Mustang. My final years I swapped my Mustang for Uncle's 351C 71 LTD I bought off him. The 1,100+ mile ride was pretty much a pour myself out of the Mustang exhausted and hitting a motel to sleep. The first year in the LTD I noticed no exhaustion and I believe I was pretty much pulling the car off into a reat area, cracking the windows and snoozing in a rest area until I'd wake from a nap and finish the drive.
Amazing the difference physically driving a "cushion" vs a rumbling muscle car.
Bill Warner (head honcho Amelia Island Concours d'Elegance) told me about renting a brand new Lincoln Town Car and driving it in the first One-Lap Of America and handing it back to a freaked out Hertz with about 10,000+ miles added to the odometer in less than a week.