When Holley first announced carb-replacement TBI, I was writing for Super Ford Magazine. I arranged to apply the very first dual four-barrel system to Brother Lon's '67 Mustang/427 combo. It took some parts swapping and some custom-fabricated parts to get the final combo together, and Jim Dove worked with me to create a set of TP components that included a factory dual-plane manifold first designed for the LeMans GT-40 effort.
The TBI systems now available are light years beyond those first systems in precision tunability and ease of use. I have no hesitation in suggesting that you look in that direction.
KS