I ran a Hampton 8-71 blower on a 452 inch FE motor for about 10 years on my Mustang. It was ridiculously fun!
They are very violent and hit quite hard when you "put it to the wood!"
Couple of things. If your blower has a nostalgia type 1/2" pitch drive, I started with a 35 tooth pulley on the bottom and a 40 on top. Then sneak up on the boost. At 1:1, or 35 teeth top and bottom, my motor made 12-13 pounds of boost. Autometer makes a tattle-tale device that you install with your boost gauge to let you know highest boost achieved. Get one.
If you have shiny ceramic coated headers on your car they will turn a dull gray soon after first start-up.
As far as camshafts go my experience is that blown motors don't care much. If you're going to get a "blower cam" with really wide lobe separation and 8-10 more exhaust duration, get a regrind from Ken at Oregon Cams. He's a good guy. I had a big (.640 lift) and a small (.575 lift) cam and couldn't tell the difference.
Use a steel crank. I ran an iron 1UB 428 crank for a few years. Broke it right behind the first main journal.
Use 2 big carburetors and have Faron, a member here with a roots blown Mustang, set them up with boost referenced power valves. Really, do it! I ran 2 Holley 950HP's. The blower won't care how big...just if they're too small. I would not go smaller than 2 750DP's. Go for Dominators!
Roots blown motors love advanced timing, lots of it, until they don't. Use some kind of computer controlled timing device that pulls timing out buy either RPM or boost level. I always ran 100LL AVgas in mine but did eventually put a Snow water/meth system on.
No room for the ignition distributor, I used an Electromotive crank trigger waisted spark deal. It's still working fine.
Lots of other small stuff you'll figure out. Like that huffer is REALLY HEAVY! Think you're going to bend over the fender and lift an 8-71 off the motor by yourself...you're dream'n!
Have fun!