There can be harm running a PCV valve, if your engine is on the brink of detonation. Oil mist is sucked into the intake tract with a PCV, and that makes the mixture more prone to detonation. I never use PCV valves for that reason. Also, use of the PCV valve does not automatically remove oil mist from the engine compartment, sometimes you will get mist out of the lone breather anyway. A PCV valve will improve that situation in most cases, though.
A better, albeit more complex solution to this issue, is to use a pan evac system, where the valve cover breathers are connected to tubes that run down to the header collectors. In that case you don't have any crankcase openings to the engine compartment, so no oil mist, and no oil gets into the intake tract to encourage detonation. Plus you get the added benefit of a few inches of crankcase vacuum. I've had good luck running those systems on the street and at the track, but it's a lot more work to install.