That Aeromotive diagram just confuses people. Their stuff is all over the place - one pump uses -10 AN for 1500 HP, the next uses -12 AN in -10 AN out for 2000 HP, then they recommend a return reg that either won't go below 18 PSI or uses a #8 return which may or may not be enough when you're feeding 550 HP with 420 GPH @ 7 PSI. I'm researching methanol for up to 650 HP and it's surprisingly hard to find a consensus on pumps and regulators in the 100~250 GPH ranges. That includes BLP, Aeromotive, MagnaFuel, Holley/QuickFuel, APD, Product Engineering, Weldon, etc.
More or less as above - on gas, #8 should be good to 750HP or better. Note that #10 flows more and if your fuel comes from the rear, increases in line size increase the head pressure, requiring larger pumps to move the fuel forward. That where my pipe rack has an advantage - when I leave, all the fuel up front WANTS to go back to the motor LOL. The return line has the inertia problem.