So late to the game here, but I think a lot of this is "master of the obvious" Long runners, small CSA, wedge chamber, tight bore spacing, nothing we haven't talked about before.
A couple points I'll bring up are:
The intake was a bottleneck right behind the heads, when better (
not BBC/BBF/CHI better, but better) heads came available, the available intakes became a problem, Jay's offering fixed that cheaper than sheetmetal and allowed those who want sheetmetal to not have to build a complex (and wet) custom intake. Good on Jay ...
...despite a C not being mainstream either, having the wet section of the intake separate uncomplicates things.
However, overall intake runner length, taper, CSA (not so much volume for me other than recent discussion of some small fast ports), piston speed and acceleration, valve events, etc, these are not new things to many of this crowd, in fact I think this forum more than the other sort of supports that fix. I don't love the choices I have to work with, but some of us even play with water hammer theory intake tuning and plenum sizing to the best that we can.
Good luck on the 422, I think you will like a rocker design that doesn't take a posi locks and girdles, a crank that doesn't hang below the block casting and I am looking forward to see what you come up with. Of course overlap in a wedge chamber behaves differently, valve inclination is different, low flat intake ports are different, the chamber behaves differently than a dome. No doubt with your experience you'll build a good engine, but I'd be cautious to think guys on this forum aren't thinking that way already.
Whatever you do, be sure to post your results