I had ran Nitrous on 3 different FEs, one with great results, one with so-so results, and cost me an engine, transmission, and almost, a car. The great was my numbers matching 69 R code automatic Mach 1, totally stock except for a Comp 268H cam, and F427 intake. Stock 735 carb, exhaust manifolds, torque convertor, single point ignition, 3.50 gears. "Off the bottle", the 69 ran a best of 13.38ET at 102mph, on 235/60R14 street radials, with a 100HP NOS Cheater plate setup, it ran 12.30s at 113 mph on the street tires, 11.92 on a pair of 81/2x26 MT slicks.
My 70 R code 4 speed Mach 1, a few years earlier, with a few bolts ons, ran a best of 12.52 at 111 MPH, on slicks with open headers, I then added the same NOS kit that I later put on the 69. Even with a McLeod 11 1/2" clutch and 4.30 gears, the 2.32 1rst gear would slip if I tried to launch it on the nitrous, so I ended up just using the nitrous in 3rd and 4th gear, which picked up 4 mph, but less than a tenth in the 1/4 mile. With the 69, I found that if I just ran the nitrous in 1rst and 2nd gear, it made much more improvement using the nitrous in the 1rst part of the run, than just using it for the 2nd 1/2.
The bad deal, was with my Fairmont, which in 1988 and 89, had a decent 390, with a C6. With no nitrous, the 390 ran a best on 11.42 at 117mph. I decided to take the NOS kit from my 69, and stick it on the Fairmont. With the 100HP jets, it was great, ran 10.50s at 126 MPH, launching at WOT with the nitrous on. However, like many bottle squeezers, I got hooked on the "easy" HP, so I switched to the 175HP jets. Another big improvement, went a best of 10.28 at 132 mph, until a few months later. I was at a race in Bremerton, and just before the finish line, there was a loud boom, flames out of the scoop, and I was sliding around in water at 130ish MPH. Luckily, I kept it off the guardrail, could have been a lot worse. When I took the engine apart, I found all the main webbing between the cam and main bearing bores was ripped out, the crank was in 5 sections. The rear section of crankshaft was flopping around enough that the flexplate teeth sliced a groove thru the C6s bellhousing, broke off the front pump stater support, snapped off the starter nose, and when the rear webbing broke, it tore open the rear water jackets, which is why I had the water under the slicks. When I built this engine a few years earlier, I installed brand new 427 LeMans rods, with SPS bolts, all of the rods were bent or twisted, but none broke.A few valves got bent, and one piston hit the head deck surface. That was over 30 years ago, and I have not touched the stuff since, nor do I ever plan to.