More specs on the cam would help more. Overlap, ICL, and duration mean more than lift. Overlap basically will give you a decent idea of vacuum, and duration and ICL can predict somewhat when it clears up. However, lobes and builds are all different, so it's mostly an estimate. That being said my 489 is .600 lift and EFI since 2009, but its a solid flat and not that big.
Remember, you can get anything you want at Alice's Restaurant...with the right EFI kit, you just come in and out of open and closed loop when you want. However, typically I like to hold a regularly streeted EFI build at about the vacuum levels a "no-can" power brake system would run. That tends to be 12+ inches of vacuum. If you do that, generally the EFI does it's thing pretty well once the engine has some heat in it especially
In my truck 461, I went with a mild HFT cam, 280/286 @.006 230/236 at .050 112 on 107 to match a 4x4 use, power brakes and EFI, in the Mustang it's 286/294 @.020 242/248 @ .050 110 LSA on 106, but it calls for .027 lash and I run it at .014, so it's a little bigger than it seems, and no power brakes