I see 5.0 engines pulling 500 hp with a set of heads, intake and cam. Also reprogrammed ecm and mass air flow conversion. If I can't. Get another 150 hp over that with 150 more cubes than there is something wrong. The cam more than likely will go once I get things going. Something more like 650/650 290/300 114 degree separation. Initially I bought the cam with the intension of burning E85 but decided to scrap that idea. I have the converted Edelbrock 750s and dual quad intake also but I changed plans. The block should hold fine with staying under 7000 rpm. I am sure I will exceed 600 hp no problem with 445 cubes as most modern two valve engines with current technology get between 1.25-1.5 hp per cube. Given that the heads, induction and ignition is set up properly. Even the aftermarket injection systems with a four barrel throttle body are still a step backwards that is why the OEM did away with it. Basically I am using a FE block and rotating assembly and putting a modern mustang induction and cylinder head design on it. I have built small block Ford and Chevy engines with a good set of Dart heads that made over 500 hp with under 400 cubic inches.
I specialize in Ford engines and have built a ton of FE's and a ton of SBF's, including big inch Windsors (427-445) and Clevelands. I will tell you straight up that you won't see a 5.0 Ford making 500 hp with just a head, intake, and cam swap. Desktop Dyno may tell you that, or a liberal dyno'd magazine article will tell you that, but it doesn't happen in the real world.
On the dyno I use, here's what it takes to make 650-700 hp...
1. 445 ci Windsor, with ported TFS TW-R heads that flowed about 345 cfm @ .700" lift. Cam was 260/264 @ .050" Bullet solid roller, 109 LSA, .700" net lift, ported Super Victor intake manifold, Racetec pistons with 1.5/1.5/3mm ring pack, etc, etc. It made 662 hp @ 6900 with 577 lb-ft of torque. That engine used a Callies crank, Oliver rods, Isky Red Zone lifters, stud girdle, dry sump, etc. It was around 10.7:1 compression, runs on 93 octane, Quick Fuel Q-950 carb.
2. 445 ci Windsor, with ported TFS TW-R heads. Joe Craine ported the heads for this engine and for the engine above, and I'm sure you will understand that it doesn't get any more "heart shaped" than a TW-R chamber. Cam was a 250/250 @ .050" hydraulic roller cam, with .640" lift, 112 LSA. Massaged Super Victor intake, Probe pistons, Scat crank and rods. It made 586 hp @ 6200. Quick Fuel Q-850 carb.
3. 487ci FE, with Pond heads ported by Keith Craft. These flowed right at 350 cfm @ .750" lift with 266 cfm on the exhaust side. Again, a very modern combustion chamber with good port work. Intake manifold was a ported Victor FE intake, cam was a Bullet solid roller, 263/268 @ .050", .700" net valve lift, 110 LSA. 10.7:1 compression ratio, running a custom Quick Fuel carb. It made 638 hp @ 6600 with 567 lb-ft @ 5200.
4. 487ci FE, with Pond heads ported by Keith Craft. Same flow numbers as above, intake was a Tunnel Wedge, cam was a Comp Cams solid roller, 262/268 @ .050", .700" net valve lift, 108 LSA, 10.5:1, running a pair of Quick Fuel carbs. It made 622 hp @ 6400, with 589 lb-ft @ 4600.
5. Building a 496 FE right now, with Keith Craft's Stage 3 Edelbrocks. Heads should flow between 360-370 @ .750". This is not a cheap build, with a custom Scat forged crank, Super Light, cut for SBC rod journal size, running Oliver rods, Diamond pistons with a .043/.043/3mm ring pack, cam is a Bullet solid roller 270/280 @ .050", .750" net lift, 112 LSA, with 11:1 compression and a Tunnel Wedge. This is a 7500 rpm engine, and I hope to make 700 hp with it on pump gas.
Now, I will say this....the Stuska dyno that I use is about 5-6% low compared to the Super Flow across town, and a DTS that I've used in Cincinnati. However, the point I'm trying to make is that it takes a whole lot of engine to make an honest 600 hp, and even more specialized parts than that to make 675-700.
I'm sure your heads are top notch if Barry set them up, but a heart shaped chamber is not going to make the difference between 550 hp and 675. They may flow 350 cfm as you say, but at what lift is it? .700"? .750"? What do they flow at .600"? By the time you look at your cam, factor in discrepancies in rocker arm ratio, pushrod deflection, valvetrain geometry mismatches, etc., you're probably looking at around .590" lift at the valve.
A cam with only 230° @ .050" is a truck cam in a 445. You should at least be looking at 10 degrees more duration, and probably a switch to a solid roller. FE's don't like hydraulic rollers above 6000-6200 and unless you've hooked up with Barry and snagged a set of his EMC lifters, your FE won't like the rpms either. I've built a lot of hydraulic roller FE's, and have played with oil pressure, spring pressure, lifter preload, etc., and you just can't get to the higher rpms without some specialized block work, cam profiles, valve springs (more pressure than your beehives will have), and lifters.
Again, I'm saying all of this to try and help you out, as I think you're very methodical in your planning and execution. However, you simply don't have enough engine to get into the 600's. My advice would be to shy away from the computer simulations, magazine articles, and pick the brains of a few FE specialized engine builders.