As has been said here, yes, it is almost that easy to do. I say almost because, like on any good engine build, you need to select components that will work well with each other to get the desired results. And if you want to enjoy the use of the motor for a number of years, you need that combination not to be pushed to its limits. Luckily, there are several variations that will do the trick.
As an example, look at engines that have been built by recognized shops and/or engine performance specialists. Brent is certainly one of those, but in the case I'm referring to here it was an engine built by Richard Holdener and the guys at Coast High Performance, a number of years ago. They built a 306 cid motor (forged rods & flat-top pistons), equipped with AFR 185 heads, a Comp XE274HR cam (224/232 @ .050", .555"/.565" Lift, 112 LSA), an Edelbrock Performer RPM, a Demon 650 cfm carb, and MSD ignition. It delivered 427 HP @ 6,100 RPM, and 395 lbs/ft of torque @ 4,900 RPM, when tested by Steve Brule out at Westech. In fact it was making 350+ lbs/ft from 3,250 out past 6,000 RPM, which is plenty for moving a Cougar around nicely with a 4-speed and 3.50+ gearing!